Breadcrumb trail: Home Physician Directory. back to search results Bookmark Share Profile. David J. Axelrod, MD, JD, FACP. David J Axelrod MD, JD, FACP. Julius Axelrod (May 30, – December 29, ) was an American biochemist. He won a . Solomon Snyder, Irwin Kopin, Rudi Schmid, Bruce R Conklin, Ron M Burch, Marty Zatz, Michael Brownstein, Chris Felder, Richard J Wurtman. L Street, 6th Floor Sacramento, CA Cardiac catheterization, Interventional cardiology, Myocardial infarction, Non-invasive cardiac testing, Radial artery catheterization (angiograms, angioplasty and stents through the wrist) Sutter Medical Center, Sacramento.
They treat various types of fibroids and embolization, which is a clot, air bubble or other blockage in the bloodstream. While the types of imaging procedures they perform are more invasive than x-rays done to identify broken bones, pain levels and recovery time are usually minimal.
If your primary care doctor wants to investigate your symptoms further, they may refer you to a radiologist to get an ultrasound or x-ray.
Some radiologists specialize in mammography and breast imaging, which is who you see when you need a mammogram. A Radiologist can also determine if bones are broken or fractured after any kind of accident. Radiologists are trained to perform MRIs and CT scans, both of which are used to determine the presence of diseases or disorders and help your doctor properly diagnose you.
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We encourage you to read our full Terms of Service. Axelrod has received 1 award. Rating Overview 7 Ratings. The research experience and mentorship Axelrod received from Brodie would launch him on his research career.
Brodie and Axelrod's research focused on how analgesics pain-killers work. During the s, users of non- aspirin analgesics were developing a blood condition known as methemoglobinemia.
Axelrod and Brodie discovered that acetanilide , the main ingredient of these pain-killers, was to blame. They found that one of the metabolites also was an analgesic. They recommended that this metabolite, acetaminophen paracetamol, Tylenol , be used instead. He examined the mechanisms and effects of caffeine , which led him to an interest in the sympathetic nervous system and its main neurotransmitters, epinephrine and norepinephrine.
During this time, Axelrod also conducted research on codeine , morphine , methamphetamine , and ephedrine and performed some of the first experiments on LSD. Allowed to submit some of his previous research toward his degree, he graduated one year later, in Axelrod then returned to the NIH and began some of the key research of his career.
Axelrod received his Nobel Prize for his work on the release, reuptake, and storage of the neurotransmitters epinephrine and norepinephrine , also known as adrenaline and noradrenaline.
Working on monoamine oxidase MAO inhibitors in , Axelrod showed that catecholamine neurotransmitters do not merely stop working after they are released into the synapse. Instead, neurotransmitters are recaptured "reuptake" by the pre-synaptic nerve ending, and recycled for later transmissions.
He theorized that epinephrine is held in tissues in an inactive form and is liberated by the nervous system when needed. This research laid the groundwork for later selective serotonin reuptake inhibitors SSRIs , such as Prozac , which block the reuptake of another neurotransmitter, serotonin.
In , Axelrod also discovered and characterized the enzyme catechol-O-methyl transferase , which is involved in the breakdown of catecholamines. Some of Axelrod's later research focused on the pineal gland. He and his colleagues showed that the hormone melatonin is generated from tryptophan , as is the neurotransmitter serotonin.
The rates of synthesis and release follows the body's circadian rhythm driven by the suprachiasmatic nucleus within the hypothalamus. Axelrod and colleagues went on to show that melatonin had wide-ranging effects throughout the central nervous system, allowing the pineal gland to function as a biological clock.
Many of his papers and awards are held at the National Library of Medicine. Gerard Prize in Neuroscience. Axelrod injured his left eye when an ammonia bottle in the lab exploded; he would wear an eyepatch for the rest of his life.
At his death, he was survived by two sons, Paul and Alfred, and three grandchildren. After receiving the Nobel Prize in , Axelrod used his visibility to advocate several science policy issues. President Richard Nixon created an agency with the specific goal of curing cancer. Axelrod, along with fellow Nobel-laureates Marshall W. Nirenberg and Christian Anfinsen , organized a petition by scientists opposed to the new agency, on the grounds that by focusing solely on cancer, public funding would not be available for research into other, more solvable, medical problems.
Axelrod also lent his name to several protests against the imprisonment of scientists in the Soviet Union. From Wikipedia, the free encyclopedia. Bethesda, Maryland , USA. Biographical Memoirs of Fellows of the Royal Society. Von Euler and Axelrod". Israel Journal of Medical Sciences.
J Ambul Care Manage. Aug;5(3) Profile of Dr. Solomon J. Axelrod. Interview by Theodore Goldberg. Axelrod SJ. PMID: ; [Indexed for. Dr. David J Axelrod, MD is a Doctor primarily located in Philadelphia, PA, with another office in Philadelphia, PA. He has 18 years of experience. His specialties . About Dr. David J Axelrod MD. Dr. David J Axelrod, MD is a Doctor primarily located in Huntington, NY. He has 17 years of experience. His specialties include .