Biochemical Pharmacology publishes original research findings, Commentaries and review articles related to the elucidation of cellular and tissue. Get more information about 'Biochemical Pharmacology' Journal. Check the. Recently published articles from Biochemical Pharmacology.
Pharmacology, Toxicology and Pharmaceutics Subcategory: Biochemistry, Genetics and Molecular Biology Subcategory: Online Article Publication Time. Average 9 Week s.
As such they may not reflect the journals' exact competitiveness or speed. Medical Science Duration of Peer Review: Accepted after revision Write a review. Duration of Peer Review: Seeking experience, thank you! Your review informs others about the journal.
Please feel free to share your manuscript submission experiences. Common drugs such as aspirin, acetaminophen paracetamol and ibuprofen inhibit biosynthesis of prostaglandins and reduce symptoms of disease, but may also cause side effects related to their actions. Other drugs are based leukotriene receptor antagonists e.
Bioactivation of polyunsaturated fatty acids also occur in plants and fungi where oxygenation of linoleic and linolenic acids is important for the plant-pathogen interaction and for fungal reproduction and pathogenicity. The goal of our research is to investigate the mechanism of oxygenation and bioactivation of fatty acids and to determine their biological function. We investigate mainly three groups of enzymes: These enzymes occur in man but also in important fungal pathogens, e.
Our goal is to understand how the enzymes work in order to understand their physiological and pathophysiological functions and to develop new drugs.
The latter is the main prostaglandin of human seminal fluid and occurs in high concentration in human semen, where it is formed by CYP4F8 of the seminal vesicles. All lipoxygenases contain a catalytic metal, iron in humans and plants. These fungi also contain oxygenate cyclooxygenase-related enzymes, which oxidized linoleic acid by to a series of vicinal diols 5,8-dihydroxy-, 7,8-dihydroxy-, and 8,dihydroxyoctadecadienoic acids via formation of hydroperoxides 8-hydroperoxy- and hydroperoxylinoleic acid , which likely function as sporulation hormones.
The reaction mechanism and identification of these diol synthases are described in our recent papers in The Journal of Biological Chemistry. Site-directed mutagenesis of 7,8-LDS revealed structural and mechanistic similarities to cyclooxygenases.
Read the latest articles of Biochemical Pharmacology at emaildatabase.me, Elsevier's leading platform of peer-reviewed scholarly literature. Biochemical Pharmacology is a peer-reviewed medical journal published by Elsevier. It covers research on the pharmacodynamics and pharmacokinetics of. Biochemical pharmacology can be: Pharmacology, the branch of medicine and biology concerned with the study of drug action; Biochemical Pharmacology.